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Enteric Viruses

HomeResearch GroupsEnteric Viruses
HomeResearch GroupsEnteric Viruses
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About the department

Enteric Viruses Division was earlier known as Rotavirus Division from the year 1990 to 2008. The mandate of the division is to conduct research studies on Epidemiology, diagnostics, detection, isolation, and molecular characterization of enteric viruses in acute gastroenteritis patients. Developmental strategies for oral immunization against Rotavirus infections and estimation of economic burden of diarrheal diseases. The division is engaged in conducting outbreak investigations and translational research activities. Division has also been undertaking research studies on Enterovirus associated diseases of public health concern, which includes Hand, Foot and Mouth disease, Acute hemorrhagic conjunctivitis, Acute encephalitis syndrome, Acute flaccid paralysis, acute gastroenteritis etc.

Scientists
Sr. No.Name of the staffDesignation
1Dr. Mallika Lavania Scientist D and Group Leader
2

Dr. Pradeep Sawant   

 Scientist C
3

Dr. P. N. Sorna

Scientist B


Technical Staff
Sr. No.Name of the staffDesignation
1Dr. Madhuri Joshi Sr. Technical Officer-2
2Dr. Sanjaykumar Tikute     Sr. Technical Officer-2
3Mr. Prabhakar JadhavTechnical Assistant
4
Mr. Manohar ShindeSr. Technician-1
5
Mrs. Nutan ChavanTechnician-B
Ongoing Projects

Ongoing Projects

1. Investigation of outbreaks and diagnostic services.

2. Hospital based surveillance of enteric viruses in patients with acute gastroenteritis in Pune.

3. Detection and Molecular Characterization of Potentially Zoonotic Enteric Viruses in Animals

4. Study to assess possible route of transmission of SARS-CoV-2 through faecal material of positive patients and their potential role in persistent fecal viral shedding in the environment.

5. An observation study on the prevalence of Human Papillomavirus infection and distribution of genotypes in cervical cancer patients from North East India

6. Isolation and propagation of human Norovirus strains obtained from acute gastroenteritis patients of Western India: A pilot study.

7. Evaluation of antiviral agents against Coxsackie virus A-16 (CV-A16) causing Hand, Foot and Mouth Disease (HFMD).

Significant research findings/contributions
  • Isolation of different serotypes of rotaviruses from children hospitalized for severe diarrhoea.
  • Preparation of immune goat colostrum against rotavirus and its use for prevention of rotavirus induced diarrhoea in infants and young children [US20030180372A1] US Patent .
  • Preparation of egg yolk antibodies against rotaviruses for passive immunization of humans and poultry
  • Development of indigenous diagnostic Rotavirus Antigen Capture ELISA kit for detection of group A rotavirus which is a rapid and cost effective method.
  • Development of an oral HEY (hen egg yolk) antibody formulation for prophylaxis and therapy against rotavirus diarrhea.
  • Successful culture adaptation and full genome-based characterization of neonatal RV G12P[11] strain.

Research Areas

  • Surveillance studies on Rota and non rota enteric viruses in acute gastroenteritis patients to understand the disease burden of diarrhea associated viruses, circulating virus strains.
  • Molecular characterization and Phylogenetic analysis of enteric viruses, ie., Rotaviruses A, B and C, Norovirus (Gr I, Gr II), Sapovirus, Enteric adeno virus, Astroviruses, Human Bocavirus, Sali, entero and Parecho viruses in acute gastroenteritis cases in and around Pune, Maharashtra state, Western India.
  • Investigation of diarrheal outbreaks for enteric virus etiology
  • Outbreak investigations on non- polio enterovirus associated diseases
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