NIV - Dr. Tejaswini Mahesh Deshmukh

Dr. (Mrs.) Tejaswini Mahesh Deshmukh

Designation: Scientist D

Division: Hepatitis Group

Educational qualifications: BSc, BSc (Applied) Biomedical Techniques, MSc, PhD

Date of joining ICMR-NIV: :19th February 1997

Contact: 91-20-26006890
Email: deshmukh.t@gov.in,desh_tejas19@hotmail.com,deshtejas1972@gmail.com
Office: Indian Council of Medical Research-National Institute of Virology, Pashan, Pune, Maharashtra, India - 411021

Research Interests:

Viral Diseases (Viral Hepatitis)
Development of anti-viral vaccines and diagnostics
Viral Immunology
Host-virus interactions

Awards/Honours:

ICMR International Fellowship 2013-14 for Young Biomedical Scientists; Received training on siRNA/miRNA as anti-viral targets under the supervision of late Prof. Radha K. Maheshwari, Uniformed Services University of Health Sciences (USUHS), Bethesda, Maryland, USA for 6 months (2nd January to 2nd July 2014).

ORCID ID: 0000-0001-5846-560X

Researcher ID:

Google Scholar Profile Link

Patent Filed

1.Patent application titled, “A method for developing a rapid immunochromatographic assay for identifying hepatitis e infection" App. No. 202011035352, filed on 17-08-2020 Priority Date India; published on 18-02-2022) (Inventors: Dr. T. M. Deshmukh, Ms. M. T. Dudhmal, Dr. K. S. Lole; Applicant: ICMR; Current Status: Application awaiting examination) (Source: Office of the Controller General of Patents, Designs & Trade Marks Dept. of Industrial Policy & Promotion Min. of Commerce & Industry Govt. of India, https://iprsearch.ipindia.gov.in/PatentSearch/PatentSearch/ViewApplicationStatus). International Filing Date 08-08-2021, International Application No. PCT/IN2021/050758, Publication Date 24-02-2022, Publication Number WO/2022/038629A1; Inventors: DESHMUKH, Tejaswini Mahesh DUDHMAL, Manisha Tukaram LOLE, Kavita Satish; Applicants: INDIAN COUNCIL OF MEDICAL RESEARCH. The PCT now has 157 Contracting States (Source: https://www.wipo.int/pct/en/pct_contracting_states.html) [Source: The World Intellectual Property Organization (WIPO), Headquarters: Geneva, Switzerland, https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2022038629&_cid=P11-LWRJ12-64718-1]. ITR Unit of ICMR has initiated filing a national phase application in Uganda in the context of PCT/IN2021/050758 application in March 2023.

List of Publications

1. Deshmukh TM, Shah RR, Devhare PB, Lole KS, Arankalle VA. Evaluation and Immunogenicity of Combined Liposome-Based Vaccine Candidates against Hepatitis E and B Viruses in Rhesus Monkeys. Vaccines 2024, 12(1): 53. DOI: 10.3390/vaccines12010053 Publisher: MDPI, Place: Basel (Switzerland).
2. Deshmukh TM, Dudhmal MT, Thorat NC, Sarje PD, Walimbe AM, Lole KS. Application of a truncated ORF2 protein-based ELISA for diagnosis of hepatitis E in an endemic area. Appl Microbiol Biotechnol 2022 Dec;106(24): 8259-72. doi: 10.1007/s00253-022-12271-9 Publisher: Springer-Nature, Place: Berlin. Link: https://rdcu.be/cZLiv. PMID: 36380192.
3. Deshmukh TM, Shah RR, Gurav YK, Arankalle VA. Serum immunoglobulin G subclass responses in different phases of hepatitis E virus infection. J Med Virol 2013, 85: 828-32. Issue No. 5 ISSN: 0146-6615, Publisher: Wiley-Liss, Place: New York. Link: http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1096-9071
4. Arankalle VA, Lole KS, Deshmukh TM, Srivastava SJ, Shaligram US. Challenge studies in Rhesus monkeys immunized with candidate hepatitis E vaccines: DNA, DNA-prime-protein-boost and DNA-protein encapsulated in liposomes. Vaccine 2009, 27: 1032-9. Issue No. 7 ISSN: 0264-410X, Publisher: Elsevier Science, Place: Amsterdam, The Netherlands. Link: http://www.sciencedirect.com/science/journal/0264410X
5. Deshmukh TM, Lole KS, Tripathy AS, Arankalle VA. Immunogenicity of candidate hepatitis E virus DNA vaccine expressing complete and truncated ORF2 in mice. Vaccine. 2007, 25: 4350-60. Issue No.22 ISSN: 0264-410X, Publisher: Elsevier Science, Place: Amsterdam, The Netherlands. Link: http://www.sciencedirect.com/science/journal/0264410X
6. Arankalle VA, Lole KS, Deshmukh TM, Chobe LP, Gandhe SS. Evaluation of human (genotype-1) and swine (genotype-4)-ORF-2 based ELISAs for anti-HEV IgM and IgG detection in an endemic country and search for type-4 human HEV infections. J Viral Hepatitis. 2007, 14: 435-45. Issue No.6 ISSN: 1352-0504, Publisher: Blackwell Scientific Publications, Place: Oxford; Boston. Link: http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1365-2893
7. Arankalle VA, Deshmukh TM, Chobe LP, Chadha MS, Walimbe AM. Prevalence of HGV RNA in India and phylogenetic analysis based on 5' non-coding region. Ind J Gastroenterol. 2001; 20: 13-7. Issue No.1 ISSN: 0254-8860, Publisher: Indian Society of Gastroenterology, Place: Mumbai. Link: http://link.springer.com/journal/12664
8. Arankalle VA, Gandhe SS, Deshmukh TM, Chadha MS, Walimbe AM. Prevalence and phylogenetic analysis of Transfusion Transmitted Virus DNA among Indian patients. Clin and Diag Lab Immunol, 2000; 7: 845-9. Issue No.5 ISSN: 1071-412X, Publisher: American Society for Microbiology, Place: Washington, D.C. Link: http://cdli.asm.org/

Chapters in Books:

1. Contributed 4 chapters on hepatitis E serological assays developed in house at Hepatitis Group, ICMR-NIV (HEV IgM Rapid Test, Human HEV IgM ELISA, Human HEV IgG ELISA and Swine HEV IgG ELISA) included in a handbook titled, “Made in India Technologies” published to commemorate 75 Azadi Ka Amrit Mohotsav and comply with the vision of Atmanirbhar Bharat.
2. VA Arankalle, KS Lole, AS Tripathy, TM Deshmukh. Hepatitis Viruses in NIV Golden to Diamond Jubilee: The Glorious Decade (Golden Jubilee Publication). 2012, Eds. V. A. Arankalle and D. Cecilia. ISBN: None, Publisher: National Institute of Virology, Place: Pune, Link: None.