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Dr Sreelekshmy Mohandas

HomeDr Sreelekshmy Mohandas
HomeDr Sreelekshmy Mohandas
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Dr. Sreelekshmy Mohandas

Designation: Scientist D

Division: Maximum Containment Facility

Educational qualifications: MVSc, PhD

Date of joining ICMR-NIV: :21th December 2016

  • Contact: +91-: 02026006890/ 02026006963
  • Email: sreelekshmy.m@icmr.gov.in
  • Office: Indian Council of Medical Research-National Institute of Virology Pune Maharashtra - 411001

 

Research Interests:

  • High risk viral pathogens
  • Viral pathogenesis in animal models

 

Awards/Honours:

  • Received certificate of appreciation from ICMR-National Institute of Virology in recognition of the untiring efforts, dedicated service and constant support as a COVID-19 warrior.
  • Featured in the E-SamvadPatrika of ICMR Women scientists leading India’s fight against COVID-19’ as an appreciation of her efforts for dealing with the COVID-19 pandemic in India

 

ORCID ID:0000-0001-9254-2736

Researcher ID:ABA-5975-2021

Google Scholar Profile Link

 

List of Publications
  • 1. Gokhale M, Sudeep AB, Mathapati B, Balasubramanian R, Ullas PT, Mohandas S, Patil DR, Shete AM, Gopale S, Sawant P, Jain R. Serosurvey for Nipah virus in bat population of southern part of India. Comparative Immunology, Microbiology and Infectious Diseases. 2022 Jun 1;85:101800.

    2. Mohandas S, Yadav PD, Sapkal G, Shete AM, Deshpande G, Nyayanit DA, Patil D, Kadam M, Kumar A, Mote C, Jain R. Pathogenicity of SARS-CoV-2 Omicron (R346K) variant in Syrian hamsters and its cross-neutralization with different variants of concern. EBioMedicine. 2022 May 1;79:103997.

    3. Yadav PD, Mohandas S, Shete AM, Nyayanit DA, Gupta N, Patil DY, Sapkal GN, Potdar V, Kadam M, Kumar A, Kumar S. SARS-CoV-2 Kappa Variant Shows Pathogenicity in a Syrian Hamster Model. Vector-Borne and Zoonotic Diseases. 2022 May 1;22(5):289-96.

    4. Yadav PD, Kaur H, Gupta N, Sahay RR, Sapkal GN, Shete AM, Deshpande GR, Mohandas S, Majumdar T, Yadav S, Pandit P. Zika a vector borne disease detected in newer states of India amidst the COVID-19 pandemic. Frontiers in Microbiology.:1852.

    5. Yadav PD, Gupta N, Potdar V, Mohandas S, Sahay RR, Sarkale P, Shete AM, Razdan A, Patil DY, Nyayanit DA, Joshi Y. Isolation and genomic characterization of SARS-CoV-2 omicron variant obtained from human clinical specimens. Viruses. 2022 Feb 24;14(3):461.

    6. Mohandas S, Yadav PD, Shete A, Nyayanit D, Jain R, Sapkal G, Mote C. Protective immunity of the primary SARS-CoV-2 infection reduces disease severity post re-infection with Delta variants in Syrian hamsters. Viruses. 2022 Mar 13;14(3):596.

    7. Lavania M, Joshi MS, Ranshing SS, Potdar VA, Shinde M, Chavan N, Jadhav SM, Sarkale P, Mohandas S, Sawant PM, Tikute S. Prolonged shedding of SARS-CoV-2 in Feces of COVID-19 positive patients: Trends in genomic variation in first and second wave. Frontiers in Medicine. 2022;9.

    8. Yadav PD, Sahay RR, Anukumar B, Mohandas S, Radhakrishnan C, Gokhale MD, Balasubramaniam R, Abraham P, Gupta N, Sugunan AP, Khobragade R, George K. Nipah virus outbreak in Kerala state, India amidst of COVID-19 pandemic. Frontiers in public health. 2022 Feb 17:14.

    9. Yadav P, Mohandas S, Sarkale P, Nyayanit D, Shete A, Sahay R, Potdar V, Baradkar S, Gupta N, Sapkal G, Abraham P. Isolation of SARS-CoV-2 B. 1.1. 28.2 (P2) variant and pathogenicity comparison with D614G variant in hamster model. Journal of infection and public health. 2022 Feb 1;15(2):164-71.

    10. Yadav PD, Sarkale P, Razdan A, Gupta N, Nyayanit DA, Sahay RR, Potdar V, Patil DY, Baradkar S, Kumar A, Aggarwal N, Shete A, Mohandas S. Isolation and characterization of SARS-CoV-2 Beta variant from UAE travelers. Journal of infection and public health. 2022 Feb 1;15(2):182-6.

    11. Patil DY, Mohandas S, Yadav PD. Role of syrian hamsters and nonhuman primates in covid-19 research. Indian Journal of Comparative Microbiology, Immunology and Infectious Diseases. 2021;42(1):17-29.

    12. Munivenkatappa A, Nyayanit DA, Yadav PD, Rangappa M, Patil S, Majumdar T, Mohandas S, Sinha DP, Jayaswamy MM, OmPrakash P. Identification of Phasi Charoen-Like Phasivirus in Field Collected Aedes aegypti from Karnataka State, India. Vector-Borne and Zoonotic Diseases. 2021 Nov 1;21(11):900-9.

    13. Nyayanit DA, Sarkale P, Shete-Aich A, Kumar A, Patil S, Majumdar T, Baradkar S, Gawande P, Mohandas S, Yadav PD. Possible Role of Accessory Proteins in the Viral Replication for the 20I/501Y. V1 (B. 1.1. 7) SARS CoV-2 Variant. Pathogens 2021, 10, 1586.

    14. Yadav PD, Mendiratta SK, Mohandas S, Singh AK, Abraham P, Shete A, Bandyopadhyay S, Kumar S, Parikh A, Kalita P, Sharma V. ZRC3308 monoclonal antibody cocktail shows protective efficacy in Syrian hamsters against SARS-CoV-2 infection. Viruses. 2021 Dec 3;13(12):2424.

    15. Mohandas S, Yadav PD, Shete A, Nyayanit D, Sapkal G, Lole K, et al. SARS-CoV-2 Delta Variant Pathogenesis and Host Response in Syrian Hamsters. Viruses. 2021 Sep 5;13(9):1773.

    16. Ganneru B, Jogdand H, Daram VK, Das D, Molugu NR, Prasad SD, et al. Th1 skewed immune response of whole virion inactivated SARS CoV 2 vaccine and its safety evaluation. iScience. 2021 Apr 23;24(4):102298.

    17. Jain R, Sarkale P, Mali D, Shete AM, Patil DY, Majumdar T, Suryawanshi A, Patil S, Mohandas S, Yadav PD. Inactivation of SARS-CoV-2 by gamma irradiation. The Indian journal of medical research. 2021 Jan;153(1-2):196.

    18. Mohandas S, Yadav PD, Shete-Aich A, Abraham P, Vadrevu KM, Sapkal G, et al. Immunogenicity and protective efficacy of BBV152, whole virion inactivated SARS- CoV-2 vaccine candidates in the Syrian hamster model. iScience. 2021 Feb 19;24(2):102054.

    19. Yadav PD, Ella R, Kumar S, Patil DR, Mohandas S, Shete AM, et al. Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques. Nat Commun. 2021 Dec;12(1):1386.

    20. Gokhale MD, Sreelekshmy M, Sudeep AB, Shete A, Jain R, Yadav PD, et al. Detection of possible Nipah virus infection in Rousettus leschenaultii and Pipistrellus Pipistrellus bats in Maharashtra, India. J Infect Public Health. 2021 Aug;14(8):1010–2.<?

    21. Mohandas S, Yadav PD, Nyayanit D, Shete A, Sarkale P, Hundekar S, et al. Comparison of SARS-CoV-2 Variants of Concern 202012/01 (U.K. Variant) and D614G Variant Transmission by Different Routes in Syrian Hamsters. Vector-Borne and Zoonotic Diseases. 2021 Aug 1;21(8):638–41. <?

    22. Potdar V, Cherian SS, Deshpande GR, Ullas PT, Yadav PD, Choudhary ML, et al. Genomic analysis of SARS-CoV-2 strains among Indians returning from Italy, Iran & China, & Italian tourists in India. Indian J Med Res. 2020;151(2–3):255–60

    23. Sapkal G, Shete-Aich A, Jain R, Yadav P, Sarkale P, Lakra R, et al. Development of indigenous IgG ELISA for the detection of anti-SARS-CoV-2 IgG. Indian J Med Res. 2020;151(5):444.

    24. Shete A, Mohandas S, Jain R, Yadav PD. A qualitative IgG ELISA for detection of SARS-CoV-2-specific antibodies in Syrian hamster serum samples. STAR Protocols. 2021 Jun;2(2):100573.

    25. Mukhopadhyay L, Yadav PD, Gupta N, Mohandas S, Patil DY, Shete-Aich A, et al. Comparison of the immunogenicity & protective efficacy of various SARS-CoV-2 vaccine candidates in non-human primates. Indian J Med Res. 2020; 22.

    26. Sudeep A, Mohandas S, Bhanarkar S, Ghodke Y, Sonawane P. Vector competence of Aedes vittatus (Bigot) mosquitoes from India for Japanese encephalitis, West Nile, Chandipura and Chittoor viruses. J Vector Borne Dis. 2020;57(3):234

    27. Mohandas S, Jain R, Yadav P, Shete-Aich A, Sarkale P, Kadam M, et al. Evaluation of the susceptibility of mice & hamsters to SARS-CoV-2 infection. Indian J Med Res. 2020;151(5):479.

    28. Yadav PD, Shete-Aich A, Nyayanit DA, Pardeshi P, Majumdar T, Balasubramanian R, Ullas PT, Mohandas S, Dighe H, Sawant P, Patil S. Detection of coronaviruses in Pteropus & Rousettus species of bats from different States of India. The Indian journal of medical research. 2020 Feb;151(2-3):226.

    29. Patil DR, Yadav PD, Shete A, Chaubal G, Mohandas S, Sahay RR, et al. Study of Kyasanur forest disease viremia, antibody kinetics, and virus infection in target organs of Macaca radiata. Sci Rep. 2020 Dec;10(1):12561.

    30. Sudeep A, Shil P, Charmode M, Mohandas S, Bansod S, Gokhale M, et al. Involvement of dual serotypes during a severe dengue outbreak in Wadi area, Nagpur district, Maharashtra 2017. J Vector Borne Dis. 2019;56(4):295.

    31. Nyayanit DA, Sahay RR, Sakpal GN, Shete AM, Chaubal GC, Sarkale P, Srivastava R, Mohandas S, Yadav PD. Identification and phylogenetic analysis of herpes simplex virus-1 from clinical isolates in India. Access Microbiology. 2019;1(6).

    32. Mourya DT, Yadav PD, Mohandas S, Kadiwar RF, Vala MK, Saxena AK, et al. Canine Distemper Virus in Asiatic Lions of Gujarat State, India. Emerg Infect Dis. 2019 Nov;25(11):2128–30.

    33. Sarkale P, Shrivastava A, Mohandas S, Patil SL, Kore P, Soman V, et al. Growth Kinetics of Kyasanur Forest Disease Virus in Mammalian Cell Lines and Development of Plaque Reduction Neutralization Test. Vector-Borne and Zoonotic Diseases. 2019 Aug;19(8):630–6.

 

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