NIV - Dr. Himanshu Kaushal

Dr. Himanshu Kaushal

Designation: Scientist D

Division: Influenza Group

Educational qualifications: Ph.D.

Date of joining ICMR-NIV: :16th December 2016

Contact: 91-020-26006283
Email: kaushal.h@gov.in / hkarya@gmail.com
Office: Indian Council of Medical Research-National Institute of Virology Pune Maharashtra - 411001

Research Interests:

T cell Biology
Host-immune responses against viral pathogens
Vaccinology

Awards/Honours:

Dr. S. Sriramachari Young Scientist Award, 2014, conferred by ICMR-NIP, New Delhi
National Academy of Sciences, India (NASI)-Project SRF, 2014
Indian Council of Medical Research (ICMR)-SRF, 2011
Indian Council of Medical Research (ICMR)-JRF, 2008
CSIR-UGC test for Lectureship-NET, June 2008
Graduate Aptitude Test in Engineering (GATE), 2006
Sainik School Studentship, Ministry of Defence, Govt. of India.

ORCID ID:0000-0003-0935-9039

Researcher ID:AAY-9369-2020

Google Scholar Profile Link

List of Publications

1. Kaushal H, Kartaskar RS, Chiplunkar T, Yadav PD, Awate P, Potdar VA, Khalipe MM, Saraf C, Shete AM, Sahay RR, Das S, Chandrakant SA, Alagarasu K. Cellular Immune Responses Against γ-Inactivated Antigen in the Recovered Cases of Kyasanur Forest Disease. Viral Immunol. 2024 Mar;37(2):101-106. doi: 10.1089/vim.2023.0107. Epub 2024 Feb 5.
2. Patil D, Shete A, Yadav PD, Sapkal G, Deshpande GR, Kaushal H, Mohandas S, Fulari S, Jain R, Kumar A, Abraham P. Host immune responses in aged rhesus macaques against BBV152, an inactivated SARS-CoV-2 vaccine and cross-neutralization with beta and delta variants. Front. Immunol., 28 April 2023. volume 14 - 2023 | https://doi.org/10.3389/fimmu.2023.1161571.
3. Yadav PD, Kumar S, Agarwal K, Jain M, Patil DR, Maithal K, Mathapati B, Giri S, Mohandas S, Shete A, Sapkal G, Patil DY, Dey A, Chandra H, Deshpande G, Gupta N, Abraham P, Kaushal H, Sahay RR, Tripathy A, Nyayanit D, Jain R, Kumar A, Sarkale P, Baradkar S, Rajanathan C, Raju HP, Patel S, Shah N, Dwivedi P, Singh D. Needle-free injection system delivery of ZyCoV-D DNA vaccine demonstrated improved immunogenicity and protective efficacy in Rhesus macaques against SARS-CoV-2. J Med Virol. 2023 Jan 10. doi: 10.1002/jmv.28484.
4. Yadav PD, Sahay RR, Agrawal S, Shete A, Adsul B, Tripathy S, Nyayanit DA, Manrai M, Patil DY, Kumar S, Marwah V, Sapkal GN, Shastri J, Viswanathan R, Pandit P, Mishra Y, Chavan S, Joshi Y, Kumar TA, Majumdar T, Kumar A, Patil S, Munshi R, Desai U, Kaushal H, Suryawanshi A, Dudhmal M, Gawande P, Jain R, Waghmare A, Kalele K, Vedpathak P, Yemul J, Bodke P, Kore T, Kakrani AL, Athavale P, Suryawanshi P, Patsute S, Padbidri V, Awate P, Abraham P. Clinical, immunological and genomic analysis of the post vaccinated SARS-CoV-2 infected cases with Delta derivatives from Maharashtra, India, 2021. J Infect. 2022 Apr 7:S0163-4453(22)00193-1. doi: 10.1016/j.jinf.2022.04.014.
5. Alagarasu K, Kaushal H, Shinde P, Kakade M, Chaudhary U, Padbidri V, Sangle SA, Salvi S, Bavdekar AR, D'costa P, Choudhary ML. TNFA and IL10 Polymorphisms and IL-6 and IL-10 Levels Influence Disease Severity in Influenza A(H1N1)pdm09 Virus Infected Patients. Genes (Basel). 2021 Nov 28;12(12):1914. doi: 10.3390/genes12121914.
6. Kant R, Dwivedi G, Zaman K, Sahay RR, Sapkal G, Kaushal H, Nyayanit DA, Yadav PD, Deshpande G, Singh R, Chaowdhary S, Gupta N, Kumar S, Abraham P, Panda S, Bhargava B. Immunogenicity and safety of a heterologous prime-boost COVID-19 vaccine schedule: ChAdOx1 vaccine Covishield followed by BBV152 Covaxin. J Travel Med. 2021 Oct 15:taab166. doi: 10.1093/jtm/taab166.
7. Mammen JJ, Kumar S, Thomas L, Kumar G, Zachariah A, Jeyaseelan L, et al. Factors associated with mortality among moderate and severe patients with COVID-19 in India: a secondary analysis of a randomised controlled trial. BMJ Open. 2021 Oct 4;11(10):e050571.
8. Tripathy AS, Vishwakarma S, Trimbake D, Gurav YK, Potdar VA, Mokashi ND, et al. Pro-inflammatory CXCL-10, TNF-α, IL-1β, and IL-6: biomarkers of SARS-CoV-2 infection. Arch Virol. 2021;Sep(23):1–10.
9. Sahay RR, Shete AM, Yadav PD, Patil S, Majumdar T, Jain R, et al. Sequential determination of viral load, humoral responses and phylogenetic analysis in fatal and non-fatal cases of Crimean-Congo hemorrhagic fever patients from Gujarat, India, 2019. PLoS Negl Trop Dis. 2021;15(8):e0009718.
10. Yadav PD, Ella R, Kumar S, Patil DR, Mohandas S, Shete AM, et al. Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques. Nat Commun. 2021 Dec 1;12(1).
11. Mohandas S, Jain R, Yadav P, Shete-Aich A, Sarkale P, Kadam M, et al. Evaluation of the susceptibility of mice & hamsters to SARS-CoV-2 infection. Vol. 151, Indian Journal of Medical Research. Wolters Kluwer Medknow Publications; 2020. p. 479–82.
12. Potdar V, Cherian S, Deshpande G, Ullas P, Yadav P, Choudhary M, et al. Genomic analysis of SARS-CoV-2 strains among Indians returning from Italy, Iran & China, & Italian tourists in India. Vol. 151, Indian Journal of Medical Research. Wolters Kluwer Medknow Publications; 2020. p. 255–60.
13. Potdar V, Choudhary M, Bhardwaj S, Ghuge R, Sugunan AP, Gurav Y, et al. Respiratory virus detection among the overseas returnees during the early phase of COVID-19 pandemic in India. Vol. 151, Indian Journal of Medical Research. Wolters Kluwer Medknow Publications; 2020. p. 486–9.
14. Sapkal G, Shete-Aich A, Jain R, Yadav P, Sarkale P, Lakra R, et al. Development of indigenous IgG ELISA for the detection of anti-SARS-CoV-2 IgG. Indian J Med Res. 2020 May 1;151(5):444–9.
15. Deshpande GR, Sapkal GN, Tilekar BN, Yadav PD, Gurav Y, Gaikwad S, et al. Neutralizing antibody responses to SARS-CoV-2 in COVID-19 patients. Indian J Med Res. 2020 Jul 1;152(1):82–7.
16. Agarwal A, Mukherjee A, Kumar G, Chatterjee P, Bhatnagar T, Malhotra P. Convalescent plasma in the management of moderate covid-19 in adults in India: Open label phase II multicentre randomised controlled trial (PLACID Trial). BMJ. 2020;371:1–10.
17. Patil DR, Yadav PD, Shete A, Chaubal G, Mohandas S, Sahay RR, et al. Study of Kyasanur forest disease viremia, antibody kinetics, and virus infection in target organs of Macaca radiata. Sci Rep. 2020;10(1):1–13.
18. Kulkarni R, Sapkal GN, Kaushal H, Mourya DT. Japanese Encephalitis: A Brief Review on Indian Perspectives. Open Virol J. 2018;12(Suppl-2, M8):121–30.
19. Kaushal H, Bhattacharya SK, Verma S, Salotra P. Serological and molecular analysis of leishmania infection in healthy individuals from two districts of West Bengal, India, endemic for visceral leishmaniasis. Am J Trop Med Hyg. 2017;96(6):1448–55.
20. Kaushal H, Bras-Gonçalves R, Avishek K, Kumar Deep D, Petitdidier E, Lemesre JL, et al. Evaluation of cellular immunological responses in mono- and polymorphic clinical forms of post-kala-azar dermal leishmaniasis in India. Clin Exp Immunol. 2016 Jul 1;185(1):50–60.
21. Avishek K, Kaushal H, Gannavaram S, Dey R, Selvapandiyan A, Ramesh V, et al. Gene deleted live attenuated Leishmania vaccine candidates against visceral leishmaniasis elicit pro-inflammatory cytokines response in human PBMCs. Sci Rep. 2016;6(Sep 14):33059.
22. Ramesh V, Kaushal H, Mishra AK, Singh R, Salotra P. Clinico-epidemiological analysis of Post kala-azar dermal leishmaniasis (PKDL) cases in India over last two decades: A hospital based retrospective study Infectious Disease epidemiology. BMC Public Health. 2015 Oct 26;15(1).
23. Chamakh-Ayari R, Bras-Gonçalves R, Bahi-Jaber N, Petitdidier E, Markikou-Ouni W, Aoun K, et al. In vitro evaluation of a soluble Leishmania promastigote surface antigen as a potential vaccine candidate against human leishmaniasis. PLoS One. 2014 Jan;9(5):e92708.
24. Kaushal H, Bras-Gonçalves R, Negi NS, Lemesre J-L, Papierok G, Salotra P. Role of CD8+ T cells in protection against Leishmania donovani infection in healed Visceral Leishmaniasis individuals. BMC Infect Dis. 2014 Jan;14:653.
25. Katara GK, Raj A, Kumar R, Avishek K, Kaushal H, Ansari NA, et al. Analysis of localized immune responses reveals presence of Th17 and Treg cells in cutaneous leishmaniasis due to Leishmania tropica. BMC Immunol. 2013 Jan;14:52.
26. Khandelwal K, Bumb RA, Mehta RD, Kaushal H, Lezama-Davila C, Salotra P, et al. A patient presenting with diffuse cutaneous leishmaniasis (DCL) as a first indicator of HIV infection in India. Am J Trop Med Hyg. 2011 Jul;85(1):64–5.
27. Prasad N, Ghiya BC, Bumb RA, Kaushal H, Saboskar AA, Lezama-Davila CM, et al. Heat, oriental sore, and HIV. Lancet. 2011;377(9765):610.

Book Chapter

1.Kaushal, H., Das, S., Kartaskar, R.S., Khalipe, M.M., Chiplunkar, T. (2023). Kyasanur Forest Disease: A Neglected Zoonotic Disease of India. In: Bhukya, P.L., Mhaske, S.T., Sonkar, S.C. (eds) Emerging Human Viral Diseases, Volume I. Springer, Singapore. https://doi.org/10.1007/978-981-99-2820-0_16
2.Poonam Salotra, HimanshuKaushal, V Ramesh (2016). Containing Post Kala-azar Dermal Leishmaniasis (PKDL): Pre-requisite for sustainable elimination of Visceral Leishmaniasis (VL) from South Asia. Chapter in “Kala-azar in South Asia; Current Status and Sustainable Challenges”, P 7-21, Ed, Eisei Noiri & T.K. Jha, Springer International Publishing.