Now loading.
Please wait.

Menu

Dr. Deepti Parashar

HomeDr. Deepti Parashar
HomeDr. Deepti Parashar
single image

Dr. Deepti Parashar

Designation: Scientist F

Division:Diagnostic Reagent Facility & Dengue chikungunya group

Educational qualifications:M.Sc., Ph.D (Microbiology)

Date of joining ICMR-NIV: :14th November 2006

  • Contact: 02026006284
  • Email: Parashar.d@gov.in, deeptiparasharster@gmail.com
  • Office: Indian Council of Medical Research-National Institute of Virology Pune Maharashtra - 411001

 

Research Interests:

  • Molecular diagnostics
  • Genetic characterization
  • Antiviral testing and drug delivery systems for dengue & chikungunya virus

 

Awards/Honours:

  • Endeavour Executive Fellowship, Nano Biotechnology Research Laboratory, Centre for Advanced Materials and Industrial Chemistry, RMIT University, Melbourne, Australia (13th March - 13th July 2016)..
  • ICMR-International Fellowship, Uniformed Services University of the Health Sciences, F. Edward Hébert School of Medicine, Bethesda, MD (1stApril 2011 - 1st Oct 2011).

 

ORCID ID:0000-0003-2688-3684

Researcher ID:K-3441-2019

Google Scholar Profile Link

 

List of Publications
  • 1. Panda K, Alagarasu K, Patil P, Agrawal M, More A,  Kumar NV, Mainkar PS, Parashar D, Cherian S. In-vitro antiviral activity of α-Mangostin against dengue virus serotype -2 (DENV-2). Molecules 2021; 26: 3016.

  • 2. Patil P, Agrawal M, Almelkar S, Jeengar MK, More A, Alagarasu K, Kumar NV, Mainkar PS, Parashar D, Cherian S. Antiviral activity of α-Mangostin against chikungunya virus. Virol J. 2021; 18: 47.

  • 3. Panda K, Alagarasu K & Parashar D. Oligonucleotide-based approaches to inhibit dengue virus replication. Molecules 2021; 26:956

  • 4. Jeengar MK, Kurakula M, Patil P, More A, Sistla R, Parashar D. Antiviral activity of Stearylamine against chikungunya virus. Chemistry and Physics of Lipids 2021; 235:105049.

  • 5. Panda K, Alagarasu K, Cherian S & Parashar D. Prediction of potential siRNA molecules for silencing of the spike gene of Severe Acute Respiratory Syndrome Coronavirus-2. Indian J Med Res 2021; 153: 182-9.

  • 6. Alagarasu K, Kakade MB, Bachal RV, Bote M, Parashar D, Shah PS. Use of whole blood over plasma enhances the detection of dengue virus RNA: possible utility in dengue vaccine trials. Arch Virol. 2021; 166: 587-591.

  • 7. Kumar S, Singh VK, Vasam M, Patil P, Dhaked RK, Lohia NK, Ansaric AS, Parashar D, Tapryal S. An in vitro refolding method to produce oligomers of anti-CHIKV, E2-IgM Fc fusion subunit vaccine candidates expressed in E. coli. J Immunol Methods. Available online 21 September 2020, 112869.

  • 8. Kakade MB, Shrivastava N, Patil JA, Parashar D, Shah PS, ·Alagarasu K. Clinical evaluation of an in‑house‑developed real‑time RT‑PCR assay for serotyping of dengue virus. Arch Virol 2020; https://doi.org/10.1007/s00705-020-04725-0.

  • 9. Newase P, More A, Patil J, Patil P, Jadhav S, Alagarasu K, Shah P, Parashar D, Cherian S. Chikungunya phylogeography reveals persistent global transmissions of the Indian Ocean Lineage from India in association with mutational fitness. Inf Gen Evol 2020;  82: 1042892 https://doi.org/10.1016/j.meegid.2020.104289

  • 10. Parashar D, Rajendran V, Ramakrishna S, Shukla R. Lipid-based nanocarriers for delivery of small interfering RNA for therapeutic use. Eur J Pharm Sci 2020; 142:105159.

  • 11. Sudeep AB, Vyas PB, Parashar D and Shil P. Differential susceptibility and replication potential of certain cell lines and one mosquito species to three lineages of chikungunya virus. Indian J Med Res. 2019; 149: 771-7.

  • 12. Alagarasu K, Patila JA, Kakade, More AM, Bote M, Chowdhury D, Seervi M, Rajesh NT, Ashok M, Anukumar B, Abrahame AM, Parashar D, Shah PS. Spatio-temporal distribution analysis of circulating genotypes of dengue virus type 1 in western and southern states of India by a one-step real-time RT-PCR assay Inf Gen Evol. 2019; 75: 103989.

  • 13. Alagarasu K, Jadhav SM, Bachal RV, Bote M, Kakade MB, Ashwini M, Singh A Parashar D. Scenario of dengue and chikungunya in Pune district, Maharashtra during 2016: A retrospective study based on data from samples referred to an Apex referral laboratory. Dengue Bulletin 2018; 40:33-43.

  • 14. Abraham PR, Parashar D, Kasetty S, Sharma VD, Shivannavar CT. Characterization of nontuberculous mycobacteria isolated from environmental samples in Kalaburagi district of South India. JSM Mirobiol 2018; 6: 1051.

  • 15. Patil JA, Alagarasu K, Kakade MB, More AM, Gadekar KA, Jadhav SM, Parashar D, Shah PS. Emergence of dengue virus type 1 and type 3 as dominant serotypes during 2017 in Pune and Nashik regions of Maharashtra, Western India. Inf Gen Evol 2018; 66: 272-83.

  • 16. Chauhan DS, Sharma R, Parashar D, Das R, Sharma P, Singh AV, Singh PK, Katoch K and Katoch VM. Rapid detection of Ethambutol Resistant Mycobacterium tuberculosis in clinical specimens by real time polymerase chain hybridization probe methods. Indian J Med Mirobiol 2018; 36: 211-6.

  • 17. Parashar D, Paingankar M, More A, Patil P. Altered microRNA expression signature in Chikungunya-infected mammalian fibroblast cells. Virus Genes 2018 https://doi.org/10.1007/s11262-018-1578-8.

  • 18. Parashar D, Sudeep AB, More A, Patil P, Walimbe A, Mavale M, Amdekar S. Persistence of chikungunya virus in serum samples and infected mosquitoes stored at different temperatures. Current Science 2018; 115: 25-27.

  • 19. Patil J, More A, Patil P, Jadhav S, Newase P, Agarwal M, Amdekar S, Raut CG, Parashar D, Cherian S. Genetic characterization of chikungunya viruses based on the E1 and E2 genes during the 2015-2017 outbreaks in different States of India. Arch Virol 2018; 163:3135-3140.

  • 20. Amdekar S, Parashar D, Alagarasu K. Chikungunya virus induced arthritis: Role of host and viral factors in the pathogenesis Viral immunology 2017 30: 691-702.

  • 21. Deoshatwar AR, Parashar D, Gokhale MD, More A. Low intensity Chikungunya outbreak in rural Western India indicates potential for similar outbreaks in other regions. Asian Pac J Trop Dis 2017; 7: 401-4.

  • 22. Penumarthi A, Parashar D, Abraham AN, Dekiwadia C, Macreadie I, Shukla R and Smooker PM. Solid lipid nanoparticles mediated non-viral delivery of plasmid DNA to dendritic cells. J Nanoparticles Res. 2017; 19: 210. DOI 10.1007/s11051-017-3902-y.

  • 23. Parashar D and Cherian S. RNA interference agents as Chikungunya virus therapeutics. Future Virol 2016; 11: 321-9.

  • 24. Damle RG, Jayaram N, Kulkarni SM, Nigade K, Khutwad K, Gosavi S and Parashar D. Diagnostic potential of monoclonal antibodies against the capsid protein of chikungunya virus for detection of recent infection. Arch Virol 2016. DOI 10.1007/s00705-016-2829-4.

  • 25. Chauhan DS, Sharma R, Parashar D, Sharma P, Das R, Chahar M, Singh A, Singh PK, Katoch K and Katoch VM. Early detection of multidrug resistant (MDR) Mycobacterium tuberculosis in a single tube with in-house designed fluorescence resonance energy transfer (FRET) probes using real-time PCR. Indian J Exp Biol 2016; 54: 229-36.

  • 26. Penumarthi A, Parashar D, Shukla R, Macreadie I and Smooker PM. Utilizing novel nanoparticles for DNA vaccine delivery. J Vaccines & Vaccination 12th Asia Pacific Global Summit and Expo on Vaccines & Vaccination. November 24-25, 2016 Melbourne, Australia J Vaccines Vaccin DOI: 10.4172/2157-7560.C1.045.

  • 27. Parashar D, Amdekar S, More A, More R, Patil P and Ravindra Babu V. Chikungunya fever outbreak in Guntur, Andhra Pradesh, India (2013) Indian J Med Res (Supplement) 2015; 142 : 62-6.

  • 28. Gokhale MD, Paingankar MS, Sudeep AB and Parashar D. Chikungunya virus susceptibility and variation in populations of Aedes aegypti (Diptera: Culicidae) mosquito from India. Indian J Med Res (Supplement) 2015; 142: 33-43.

  • 29. Dayaraj C, Kakade M; Alagarasu K, Patil J, Salunke A, Parashar D and Shah PS. Development of a quantitative multiplex reverse transcriptase polymerase chain reaction for detecting dengue virus and Chikungunya virus. Archives Virol 2015;160: 323-27.

  • 30. Parashar D, Paingankar MS, Sudeep AB, More A, Shinde S and VA Arankalle. Assessment of qPCR, nested RT-PCR and ELISA techniques in diagnosis of Chikungunya. Current Science 2014; 107:2011-13.

  • 31. Desikan P, Panwalkar N, Parashar D, Trivedi SK and Chauhan DS. Massive pericardial effusion caused by Mycobacterium simiae: First case report. J Med Microbiol Case Reports. 2014. http://jmmcr.sgmjournals.org/content/1/3/e001040.full.pdf.

  • 32. Parashar D and Cherian S. Antiviral Perspectives for Chikungunya Virus. Biomed Res Int 2014; 2014: 631642. http://dx.doi.org/10.1155/2014/631642.

  • 33. Parashar D, Paingankar MS, Kumar S, Gokhale MD, Sudeep AB, Shinde SB and Arankalle VA. Administration of E2 and NS1 siRNAs inhibit Chikungunya virus replication in vitro and protects mice infected with the virus. PLoS Negl Trop Dis 2013. 7: e2405.

  • 34. Parashar D and Patil D. Chikungunya: A disease re-emerged in India after 32 years. A review in Diamond jubilee publication of NIV Commemorative compendium 2012.

  • 35. Mavale M, Sudeep AB, Gokhale MD, Hundekar SL, Parashar D, Ghodke YS, Arankalle VA and Mishra AC. Persistence of viral RNA in Chikungunya virus infected Aedes aegypti (Diptera: Culicidae) mosquitoes after prolonged storage at 280C  Am J Trop Med Hyg. 2012; 86:178-80.

  • 36. Parashar D, Khalkar P and Arankalle VA. Survival of Hepatitis A and E Viruses in Soil Samples. Clin Micro Infect. 2011; 17: E1-E4.

  • 37. Mavale M, Parashar D, Sudeep AB. Gokhale MD, Ghodke Y, Geevarghese G, Arankalle VA and Mishra AC. Venereal transmission of Chikungunya virus. Am J Trop Med Hyg 2010; 83:1242-4.

  • 38. Jadaun GPS, Upadhyay P, Ahmed Z, Das R, Parashar D, Chauhan DS, Sharma VD, and Katoch VM. Utility of IS1245-IS1311 based PCR typing system for Mycobacterium avium isolates obtained from clinical and environmental sources. J Bacteriol Res 2010; 2: 005-8.

  • 39. Parashar D, Das R, Chauhan DS, Sharma VD, Lavania M, Yadav VS, Chauhan SV and Katoch VM. Identification of environmental mycobacteria isolated from Agra, north India by conventional & molecular approaches. Indian J Med Res. 2009; 129: 424-31.

  • 40. Sudeep AB, Parashar D, Jadi RS, Basu A, Mokashi C, Arankalle VA and Mishra AC. Establishment and characterization of a new Aedes aegypti (L.) (Diptera: Culicidae) cell line with special emphasis on virus susceptibility. In Vitro Cell Dev Biol Anim. 2009; 45: 491-5.

  • 41. Dave S, Faujdar J, Kumar P, Gupta P, Das R, Parashar D, Chauhan DS, Natrajan M, Gupta UD, Katoch VM. Comparative growth pattern of multi drug resistance versus susceptible isolates of Mycobacterium tuberculosis in mice lungs. Indian J Med Res 2009; 130: 58-62.

  • 42. Rajeshwari H, Nagveni S, Ajay Oli, Parashar D, Chandrakanth KR. Morphological changes of Klebsiella pneumoniae in response to Cefotaxime: a scanning electron microscope study. World J Microbiol Biotechnol 2009; 25: 2263-6.

  • 43. Sudeep AB and Parashar D. Chikungunya: an overview. J Biosci 2008; 33:443-9.

  • 44. Lavania M, Katoch K, Parashar D, Sharma P, Das R, Chauhan DS, Sharma VD and Katoch VM. Predominance of Mycobacterium fortuitum-chelonae complex in Ghatampur field area, endemic for leprosy. Indian J Lepr 2008; 80: 323-30.

  • 45. Parashar D, Das R, Sharma VD, Chauhan DS and Katoch VM. Pathogenic rapidly growing: Mycobacterium manitobense in the environment of Agra, north India. Indian J Med Res 2007; 126: 230-2.

  • 46. Chauhan DS, Sharma VD, Parashar D, Chauhan A, Singh D, Singh HB, Das R, Aggarwal BM, Malhotra B, Jain A, Sharma M, Kataria VK, Aggarwal JK, Hanif M, Shahani A and Katoch VM. Molecular typing of Mycobacterium tuberculosis isolates from different parts of India based on IS6110 element polymorphism using RFLP analysis. Indian J Med Res 2007; 125: 577-81.

  • 47. Katoch VM, Parashar D, Chauhan DS, Singh D, Sharma VD and Ghosh S. Rapid identification of mycobacteria by gene amplification restriction analysis technique targeting 16S-23S ribosomal RNA internal transcribed spacer & flanking region. Indian J Med Res 2007; 125: 155-62.

  • 48. Parashar D, Chauhan DS, Sharma VD and Katoch VM. Applications of real-time PCR technology to mycobacterial research. Indian J Med Res 2006; 124: 385-98.

  • 49. Parashar D, Srivastava RK, Chauhan DS, Sharma VD, Singh M, Lavania M, Chauhan A, Bhatia AK and Katoch VM. Characterization of mycobacteria isolated from bovines by PRA-targetting hsp 65 gene region. J Commun Dis 2006; 38: 263-8.

  • 50. Parashar D, Chauhan DS, Sharma VD, Chauhan A, Chauhan SV and Katoch VM. Optimization of procedures for isolation of mycobacteria from soil and water samples obtained in northern India. Appl Environ Microbiol 2004; 70: 3751-3.

  • 51. Chauhan A, Chauhan DS, Parashar D, Gupta P, Sharma VD, Sachan AS, Gupta R, Agarawal BM and Katoch VM. DNA fingerprinting of Mycobacterium tuberculosis isolates from Agra region by IS 6110 probe. Indian J Med Microbiol 2004; 22: 238-40.

  • 52. Chauhan DS, Parashar D, Das R, Sharma VD and Katoch VM. Confirmation of identification of non-tuberculous mycobacterial isolates by using 165 rRNA sequencing. J Immunol Immunopathol 2004; 6: 83-84.

  • 53. Parashar D, Chauhan DS, Sharma VD, Chauhan A, Chauhan SVS and Katoch VM. Identification of mycobacteria at species level by PCR and restriction enzyme analysis by hsp65 gene. J Immunol Immunopathol 2004; 6: 84-85.

  • 54. Chauhan A, Parashar D, Chauhan DS, Sharma VD, Agarwal BM and KatochVM. PCR-ribotyping of pathogenic mycobacteria by an amplified ribosomal DNA fingerprinting assay. J Immunol Immunopathol 2004; 6: 139-140.

  • 55. Katoch VM, Sharma VD, Chauhan DS, Singh D, Parashar D, Chauhan A and Gupta A. Protocol for rapid identification of pathogenic mycobacteria by gene amplification-Ribotyping. (2004).

  • 56. Chauhan DS, Sharma VD, Singh HB, Das R, Parashar D, Chauhan A and Katoch VM (2003) DNA fingerprinting of Mycobacterium tuberculosis strains isolated from Northern parts of India using IS-6110 probe. In : Proceedings of the National Symposium on Biochemical Sciences : Health and Environmental Aspects (BSHEA-2003) (Ed. Satya  Prakash, Faculty of Science, Dayalbagh Educational Institute -Deemed University, Agra), Allied Publishers Pvt. Ltd, New Delhi, p429-30.

  • 57. Parashar D, Chauhan DS, Sharma VD, Das R, Singh HB, Chauhan A and Katoch VM (2003) Genomic analysis of variation in pathogenic mycobacteria by amplified ribosomal DNA fingerprinting techniques. In: Proceedings of the National Symposium on Biochemical Sciences: Health and Environmental Aspects (BSHEA-2003) (Ed. Satya Prakash, Faculty of Science, Dayalbagh Educational Institute -Deemed University, Agra), Allied Publishers Pvt. Ltd, New Delhi, p441-2.

  • 58. Parashar D and Singh M. Gene amplification based methods for characterization of mycobacteria. Central JALMA Institute of Leprosy Quarterly Bulletin (2003).

 

All for Joomla All for Webmasters