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Dr. Rima Rakeshkumar Sahay

HomeDr. Rima Rakeshkumar Sahay
HomeDr. Rima Rakeshkumar Sahay
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Dr. Rima Rakeshkumar Sahay

Designation: Scientist-D (Medical)

Division: Maximum Containment Facility [BSL-4 Facility]

Educational qualifications: MD [Community Medicine], DNB, DHRM, PGDHIM, PGDHHM

Date of joining ICMR-NIV: :09th january 2017

  • Contact: +91-: 020-26006960
  • Email: sahay.rr@gov.in
  • Office: Indian Council of Medical Research-National Institute of Virology Pune Maharashtra - 411001

 

Research Interests:

  • Epidemiology and outbreak containment response for high risk viral pathogens. Involved in outbreak preparedness responses including Biosafety
  • Biocontainment and Biorisk mitigation.

 

Awards/Honours:

  • Women Warriors of ICMR Women scientists leading India’s fight against COVID-19’ as an appreciation of her efforts for dealing with the COVID-19 pandemic in India at page no 15, March 2021, Featured in the E-SamvadPatrika of ICMR
  • For exemplary services during SARS-CoV-2 Pandemic from Director ICMR-NIV, Pune, 5th February 2021, Certificate of appreciation
  • For exemplary services during Nipah virus outbreak in Kerala from the Secretary DHR and DG, ICMR , 4th November 2019, Awarded Medal and Certificate
  • For the contribution in containment of Nipah outbreak in Kozhikode District of Kerala state, May 2018, Awarded Medal and Certificate

 

ORCID ID:0000-0003-1492-5568

Researcher ID:ABA-3815-2021

Google Scholar Profile Link

 

List of Publications
  • 1. Kant R, Dwivedi G, Zaman K, Sahay RR, Sapkal G, Kaushal H, Nyayanit DA, Yadav PD, Deshpande G, Singh R, Chaowdhary S, Gupta N, Kumar S, Abraham P, Panda S, Bhargava B. Immunogenicity and safety of a heterologous prime-boost COVID-19 vaccine schedule: ChAdOx1 vaccine Covishield followed by BBV152 Covaxin. J Travel Med. 2021 Oct 15:taab166. doi: 10.1093/jtm/taab166. Epub ahead of print. PMID: 34652440.

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    2. Yadav PD, Sahay RR, Sapkal G, Nyayanit D, Shete AM, Deshpande G, Patil DY, Gupta N, Kumar S, Abraham P, Panda S, Bhargava B. Comparable neutralization of SARS-CoV-2 Delta AY.1 and Delta with individuals sera vaccinated with BBV152. J Travel Med. 2021 Sep 28:taab154. doi: 10.1093/jtm/taab154. Epub

  •  3. Patil DR, *Yadav PD, Shete A, Chaubal G, Mohandas S, Sahay RR, Jain R, Mote C, Kumar S, Kaushal H, Kore P, Patil S, Majumdar T, Fulari S, Suryawanshi A, Kadam M, Pardeshi PG, Lakra R, Sarkale P, Mourya DT. Study of Kyasanur forest disease viremia, antibody kinetics, and virus infection in target organs of Macaca radiata. Sci Rep. 2020 Jul 28; 10(1):12561. DOI: 10.1038/s41598-020-67599-x. PMID: 32724103; PMCID: PMC7387489.

  •  4. Gupta N, Kaur H, Yadav PD, Mukhopadhyay L, Sahay RR, Kumar A, Nyayanit DA, Shete AM, Patil S, Majumdar T, Rana S. Clinical Characterization and Genomic Analysis of Samples from COVID-19 Breakthrough Infections during the Second Wave among the Various States of India. Viruses. 2021 Sep;13(9):1782

  • 5. Sahay RR, Shete AM, Yadav PD, Patil S, Majumdar T, Jain R, et al. (2021) Sequential determination of viral load, humoral responses and phylogenetic analysis in fatal and non-fatal cases of Crimean-Congo hemorrhagic fever patients from Gujarat, India, 2019. PLoS Negl Trop Dis 15(8): e0009718.

    https://doi.org/10.1371/journal.pntd.0009718  

  • 6. Munivenkatappa A, *Yadav PD, Swetha K, Jayaswamy M, Nyayanit DA, Sahay RR, Basavaraj TJ. SARS-CoV-2 & influenza A virus co-infection in an elderly patient with pneumonia. Indian J Med Res. 2021 Jan 12. DOI: 10.4103/ijmr.IJMR_2711_20. Epub ahead of print. PMID: 33433500.

  • 7. Sapkal GN, Yadav PD, Ella R, Deshpande GR, Sahay RR, Gupta N, Mohan VK, Abraham P, Panda S, Bhargava B. Inactivated COVID-19 vaccine BBV152/COVAXIN effectively neutralizes recently emerged B 1.1.7 variant of SARS-CoV-2. J Travel Med. 2021 Mar 27:taab051. doi: 10.1093/jtm/taab051. Epub ahead of print. PMID: 33772577; PMCID: PMC8083765.

  • 8. *Yadav PD, Nyayanit DA, Sahay RR, Sarkale P, Pethani J, Patil S, Baradkar S, Potdar V, Patil DY. Isolation and characterization of the new SARS-CoV-2 variant in travellers from the United Kingdom to India: VUI-202012/01 of the B.1.1.7 lineage, Journal of Travel Medicine, Volume 28, Issue 2, March 2021, taab009,

    DOI: https://doi.org/10.1093/jtm/taab009

  • 9. *Yadav PD, Nyayanit DA, Sahay RR, Shete AM, Majumdar T, Patil S, Patil DY, Gupta N, Kaur H, Aggarwal N, Vijay N, Narayan J, Nikam C, Pethani J. Imported SARS-CoV-2 V501Y.V2 variant (B.1.351) detected in travelers from South Africa and Tanzania to India. Travel Med Infect Dis. 2021 Mar 13:102023. DOI:10.1016/j.tmaid.2021.102023. Epub ahead of print. PMID: 33727176; PMCID: PMC7955805.

  • 10. Mourya DT, Yadav PD, Patil DY, Sahay RR, Rahi M. Experiences of Indian Council of Medical Research with tick-borne zoonotic infections: Kyasanur Forest disease & Crimean-Congo haemorrhagic fever in India with One Health focus. Indian Journal of Medical Research. 2021 Mar 1;153(3):339. (Review)

  • 11. *Yadav PD, Sapkal GN, Abraham P, Ella R, Deshpande G, Patil DY, Nyayanit D, Gupta N, Sahay RR, Shete AM, Panda S, Bhargava B, V. Krishna Mohan. Neutralization of variant under investigation B.1.617 with sera of BBV152 vaccinees, Clinical Infectious Diseases, 2021;, ciab411, https://doi.org/10.1093/cid/ciab411

  • 12*Yadav PD, Sapkal GN, Abraham P, Deshpande G, Nyayanit D, Patil DY, Gupta N, Sahay RR, Shete A, Kumar S, Panda S, Bhargava B. Neutralization potential of Covishield vaccinated individuals sera against B.1.617.1. Clinical Infectious Diseases, 2021;, ciab483, https://doi.org/10.1093/cid/ciab483

  • 13. *Yadav PD, Sapkal GN, Ella R, Sahay RR, Nyayanit DA et al. Neutralization against B.1.351 and B.1.617.2 with sera of COVID-19 recovered cases and vaccinees of BBV152. Journal of travel medicine. taab104, https://doi.org/10.1093/jtm/taab104

  • 14. Yadav PD, Nyayanit DA, Majumdar T, Patil S, Kaur H, Gupta N, Shete AM, Pandit P, Kumar A, Aggarwal N, Narayan J, Vijay N, Kalawat U, Sugunan AP, Munivenkatappa A, Sharma T, Devi S, Majumdar T, Jaryal S, Bakshi R, Joshi Y, Sahay R, Shastri J, Singh M, Kumar M, Rawat V, Dutta S, Yadav S, Krishnasamy K, Raut S, Biswas D, Borkakoty B, Verma S, Rani S, Deval H, Patel D, Turuk J, Malhotra B, Fomda B, Nag V, Jain A, Bhargava A, Potdar V, Cherian S, Abraham P, Gopal A, Panda S, Bhargava B. An Epidemiological Analysis of SARS-CoV-2 Genomic Sequences from Different Regions of India. Viruses 2021, 13, 925. https://doi.org/10.3390/v13050925.

  • 15. Cherian S, Potdar V, Jadhav S, Yadav P, Gupta N, Das M, Rakshit P, Singh S, Abraham P, Panda S, Team NIC. SARS-CoV-2 Spike Mutations, L452R, T478K, E484Q and P681R, in the Second Wave of COVID-19 in Maharashtra, India. Microorganisms. 2021 Jul 20;9(7):1542. doi: 10.3390/microorganisms9071542. PMID: 34361977; PMCID: PMC8307577.

  • 16. Sudeep AB, *Yadav PD, Gokhale MD, Balasubramanian R, Gupta N, Shete A, Jain R, Patil S, Sahay RR, Nyayanit DA, Gopale S. Detection of Nipah virus in Pteropus medius in 2019 outbreak from Ernakulam district, Kerala, India. BMC infectious diseases. 2021 Dec; 21(1):1-7.

  • 17. *Yadav PD, Sapkal GN, Ella R, Sahay RR, Nyayanit DA, Patil DY, Deshpande G, Shete AM, Gupta N, Mohan VK, Abraham P. Neutralization of Beta and Delta variant with sera of COVID-19 recovered cases and vaccinees of inactivated COVID-19 vaccine BBV152/Covaxin. Journal of Travel Medicine. 2021 Jul 6. taab104, https://doi.org/10.1093/jtm/taab104

  • 18. Sapkal G, *Yadav PD, Sahay RR, Deshpande G, Gupta N, Nyayanit DA, Patil DY, Kumar S, Abraham P, Panda S, Bhargava B. Neutralization of Delta variant with sera of Covishield vaccinees and COVID-19 recovered vaccinated individuals. Journal of Travel Medicine, taab119, https://doi.org/10.1093/jtm/taab119

  • 19. Sahay RR, Dhandore S, *Yadav PD, Chauhan A, Bhatt L, Garg V, Gupta N, Nyayanit DA, Shete AM, Singh R, Patil S, Sharma H, Meena D, Gupta J, Gawande P, Kalele K, Jain R, Mali D, Malhotra B, Nag V, Khatri PK, Kaur H, Vijay N, Singh S, Gopalakrishnan M. Detection of African genotype in Hyalomma tick pools during Crimean Congo hemorrhagic fever outbreak, Rajasthan, India, 2019. Virus Res. 2020 Sep; 286:198046. DOI: 10.1016/j.virusres.2020.198046. Epub 2020 Jun 4. PMID: 32505728.

  • 20. Tripathi S, Bhati R, Gopalakrishnan M, Bohra GK, Tiwari S, Panda S, Sahay RR, Yadav PD, Nag VL, Garg MK. Clinical profile and outcome of patients with Crimean Congo haemorrhagic fever: a hospital based observational study from Rajasthan, India. Trans R Soc Trop Med Hyg. 2020 Sep 1; 114(9):643-649. DOI: 10.1093/trstmh/traa014. PMID: 32286662.

  • 21. Agarwal A, Nagi N, Chatterjee P, Sarkar S, Mourya D, Sahay RR, Bhatia R. Guidance for building a dedicated health facility to contain the spread of the 2019 novel coronavirus outbreak. Indian J Med Res 2020;151:177-83

  • 22. Mourya DT, Yadav PD, Ullas PT, Bhardwaj SD, Sahay RR, Chadha MS, Shete AM, Jadhav S, Gupta N, Gangakhedkar RR, Khasnobis P, Singh SK. Emerging/re-emerging viral diseases & new viruses on the Indian horizon. Indian J Med Res. 2019 Apr; 149(4):447-467. DOI: 10.4103/ijmr.IJMR_1239_18. Erratum in: Indian J Med Res. 2019 May; 149(5):688. PMID: 31411169; PMCID: PMC6676836. (Review)

  • 23. Yadav PD, Malhotra B, Sapkal G, Nyayanit DA, Deshpande G, Gupta N,  Ullas P T, Sharma H,  Sahay RR, Sharma P, Mourya DT. Zika virus outbreak in Rajasthan, India in 2018 was caused by a virus endemic to Asia Infection, Infection, Genetics and Evolution. 69. 10.1016/j.meegid.2019.01.026

  • 24. *Yadav PD, Shete AM, Kumar GA, Sarkale P, Sahay RR, Radhakrishnan C, et al. Nipah Virus Sequences from Humans and Bats during Nipah Outbreak, Kerala, India, 2018. Emerg Infect Dis. 2019 May; 25(5):1003-1006. DOI: 10.3201/eid2505.181076. PMID: 31002049; PMCID: PMC6478210.

  • 25. Nyayanit DA, Sahay RR, Sakpal GN, Shete AM, Chaubal GC, Sarkale P, Srivastava R, Mohandas S, *Yadav PD. Identification and phylogenetic analysis of herpes simplex virus-1 from clinical isolates in India. Microbiol. 2019 Jul 26; 1(6):e000047. DOI: 10.1099/acmi.0.000047. PMID: 32974534; PMCID: PMC7470303.

  • 26. *Yadav PD, Gurav YK, Shete AM, Jain R, Nyayanit DA, Pardeshi PG, Viswanathan R, Chiplunkar TR, Awate P, Majumdar TP, Sahay RR, Mourya DT. Kinetics of viral RNA, immunoglobulin-M & G antibodies in Kyasanur forest disease. Indian J Med Res. 2019 Aug; 150(2):186-193. DOI: 10.4103/ijmr.IJMR_1929_17. PMID: 31670274; PMCID: PMC6829781.

  • 27. Mourya DT, Yadav PD, Mohandas S, Kadiwar RF, Vala MK, Saxena AK, Shete-Aich A, Gupta N, Purushothama P, Sahay RR, Gangakhedkar RR, Mishra SCK, Bhargava B. Canine Distemper Virus in Asiatic Lions of Gujarat State, India. Emerg Infect Dis. 2019 Nov; 25(11):2128-2130. DOI: 10.3201/eid2511.190120. PMID: 31625861; PMCID: PMC6810198.

  • 28. Sahay RR, *Yadav PD, Gupta N, Shete AM, Radhakrishnan C, et al. Experiential learnings from the Nipah virus outbreaks in Kerala towards containment of infectious public health emergencies in India. Epidemiol Infect. 2020 Apr 23; 148:e90. DOI: 10.1017/S0950268820000825. PMID: 32321607; PMCID: PMC7253795.

  • 29. Sahay RR, *Yadav PD, Majumdar T, Patil S, Sarkale P, Shete AM, Chaubal G, Dange VR, Patil S, Nyayanit DA, Shastri J, Mourya DT. Clinico-epidemiological investigation on Varicella Zoster Virus indicates multiple clade circulation in Maharashtra state, India. Heliyon. 2018 Aug 28; 4(8):e00757. DOI: 10.1016/j.heliyon.2018.e00757. PMID: 30175265; PMCID: PMC6118100

  • 30. Bharadwaj SD, Sahay RR, Yadav PD, Dhanawade S, Basu A, Meena VK, George S, Damle R, Sapkal GN. Acute Encephalitis with Atypical Presentation of Rubella in Family Cluster, India. Emerg Infect Dis. 2018 Oct; 24(10):1923-1925. DOI: 10.3201/eid2410.180053. PMID: 30226166; PMCID: PMC6154155.

  • 31 .Munivenkatappa A, Sahay RR, Yadav PD, Viswanathan R, Mourya DT. Clinical & epidemiological significance of Kyasanur forest disease. Indian J Med Res. 2018 Aug; 148(2):145-150. DOI: 10.4103/ijmr.IJMR_688_17. PMID: 30381537; PMCID: PMC6206778.

  • 32. Arunkumar G, Chandni R, Mourya DT, Singh SK, Sadanandan R, Sudan P, Bhargava B. Nipah Investigators People and Health Study Group. Outbreak Investigation of Nipah Virus Disease in Kerala, India, 2018. J Infect Dis. 2019 May 24; 219(12):1867-1878. DOI: 10.1093/infdis/jiy612. PMID: 30364984.

  • 33. Yadav PD, Sahay RR, Mourya DT. Detection of Kyasanur forest disease in newer areas of Sindhudurg district of Maharashtra State. Indian J Med Res. 2018 Oct; 148(4):453-455. DOI: 10.4103/ijmr.IJMR_1292_17. PMID: 30666009; PMCID: PMC6362715.

  • 34. * Yadav PD, Sahay R, Sapkal G. Efforts towards Biosafety and dual use of Science and technology by India. ICMR Hindi Bulletin, Pp 23-25 April 2017; Year 31, order 4.ISSN: 0971-9873. Index NA 8. 2017 (Booklet)

  • 35. Sahay RR, Bansode SS, Shinde RR. Disorder of Sexual Development- 46 XXY, 2015. International Journal of Scientific Research; IV (1):304-305

  • 36. Sahay RR, Bansode SS, Shanbhag S. Leprosy- Post Elimination phase- Still a Public Health Challenge in India, 2015. Indian Journal of Applied Research; V(1): 461-463

    List of the preprints on SARS-CoV-2 published during year 2021 in Pandemic cited on https://www.icmr.gov.in/cpapers.html

  • 37. Sapkal GN, *Yadav PD, Ella R, Deshpande G, Sahay R, Gupta N, Mohan VK, Abraham P, Panda S, Bhargava B. Neutralization of UK-variant VUI-202012/01 with COVAXIN vaccinated human serum. bioRxiv. 2021 Jan 1. DOI: https://doi.org/10.1101/2021.01.26.426986

  • 38. *Yadav PD, Sarkale P, Razdan A, Gupta N, Nyayanit D, Sahay R, Potdar V, Patil D, Baradkar S, Kumar A, Aggarwal N, Shete A, Kaur H. Isolation and characterization of SARS-CoV-2 VOC, 20H/501Y.V2, from UAE travelers. bioRxiv preprint doi: https://doi.org/10.1101/2021.05.14.443968.

  • 39. *Yadav PD, Sapkal G, Abraham P, Ella R,Deshpande G, Patil D, Nyayanit D, Gupta N,Sahay R, Shete A, Panda S, Bhargava, Mohan K. Neutralization of variant under investigation B.1.617 with sera of  BBV152 vaccinees. bioRxiv preprint. doi: https://doi.org/10.1101/2021.04.23.441101.

  • 40. *Yadav PD,  Sapkal G, Abraham P, Deshpande G, Nyayanit D, Patil D, Gupta N, Sahay R,  Shete A, Kumar S, Panda S, Bhargava B. Neutralization potential of Covishield vaccinated individuals against B.1.617. 1. bioRxiv preprint. doi: https://doi.org/10.1101/2021.05.12.443645

  • 41. * Yadav PD,, Sapkal GN, Ella R, Sahay RR, Nyayanit DA et al. Neutralization against B.1.351 and B.1.617.2 with sera of COVID-19 recovered cases and vaccinees of BBV152. bioRxiv; 2021. DOI: 10.1101/2021.06.05.447177

  • 42*Yadav PD , Mohandas S, Sarkale P, Nyayanit DA, Shete AM, Sahay RR, et al. Isolation of SARS-CoV-2 B.1.1.28.2 P2 variant and pathogenicity comparison with D614G variant in hamster model . bioRxiv 2021.05.24.445424; doi: https://doi.org/10.1101/2021.05.24.445424

  • 43. Cherian S, Potdar V, Jadhav S, *Yadav PD , Gupta N, Das M, Rakshit P, Singh S, Abraham P, Panda S. NIC Team, Convergent evolution of SARS-CoV-2 spike mutations, L452R, E484Q and P681R, in the second wave of COVID-19 in Maharashtra, India. bioRxiv. 2021 Jan 1.

  • 44. Sapkal GN, *Yadav PD , Rima R. Sahay, Gururaj Deshpande, Nivedita Gupta et al. Neutralization of Delta variant with sera of Covishield vaccinees and COVID-19 recovered vaccinated individuals. bioRxiv 2021.07.01.450676; doi: https://doi.org/10.1101/2021.07.01.450676

  • 45. *Yadav PD ,  Sahay RR,  Sapkal G,  Nyayanit D,  Shete AM et al. Comparable neutralization of SARS-CoV-2 Delta AY.1 and Delta in individuals sera vaccinated with BBV152. bioRxiv 2021.07.30.454511; doi: https://doi.org/10.1101/2021.07.30.454511

  • 46. *Yadav PD , Gajanan N. Sapkal, Priya Abraham, Gururaj Deshpande, Dimpal A Nyayanit, Sahay RR et al. Neutralization potential of Covishield vaccinated individuals sera against B.1.617.1 .bioRxiv 2021.05.12.443645; doi: https://doi.org/10.1101/2021.05.12.443645

  • 47. Shrivastav RK, Dwivedi G,  Zaman K, Rima R Sahay,  Sapkal, Himanshu Kaushal, Dimpal Nyayanit,  *Yadav PD , et al. Serendipitous COVID-19 Vaccine-Mix in Uttar Pradesh, India: Safety and Immunogenicity Assessment of a Heterologous Regime.

     medRxiv 2021.08.06.21261716; doi:https://doi.org/10.1101/2021.08.06.21261716

  • 48. Yadav PD, Kumar S, Agarwal K, Jain M, Patil D, Maithal K, Mathapati B, Giri S, Mohandas S, Shete A, Sapkal G. Assessment of immunogenicity and protective efficacy of ZyCoV-D DNA vaccine candidates in Rhesus macaques against SARS-CoV-2 infection. bioRxiv. 2021 Jan 1.DOI: https://doi.org/10.1101/2021.02.02.429480

  • 49. Gupta N, Kaur H,  *Yadav PD ,  Mukhopadhyay L, Sahay RR et al, . Clinical characterization and Genomic analysis of COVID-19 breakthrough infections during second wave in different states of India.medRxiv 2021.07.13.21260273; doi:https://doi.org/10.1101/2021.07.13.21260273

 

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