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Dr. Manohar Lal Choudhary

HomeDr. Manohar Lal Choudhary
HomeDr. Manohar Lal Choudhary
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Dr. Manohar Lal Choudhary

Designation: Scientist E

Division: Influenza Group

Educational qualifications: MSc Microbiology, PhD Biotechnology

Date of joining ICMR-NIV: :27th April 2009

  • Contact: +91-020-26006270
  • Email: mlchoudhary@gmail.com, choudhary.ml@gov.in
  • Office: Indian Council of Medical Research-National Institute of Virology Pune Maharashtra - 411001

 

Research Interests:

  • Respiratory viruses surveillance
  • Host pathogen interactions,
  • Development of recombinant viral vaccine
  • viral assay development

 

Awards/Honours:

  • CSIR JRF
  • CSIR SRF
  • PDF

 

ORCID ID: 0000-0001-9968-8957

Researcher ID: ABA-6120-2021

Google Scholar Profile Link

 

List of Publications
  • 1. Potdar V, Brijwal M, Lodha R, Yadav P, Jadhav S, Choudhary ML, Choudhary A, Vipat V, Gupta N, Deorari AK, Dar L, Abraham P. Identification of Human Case of Avian Influenza A(H5N1) Infection, India. Emerg Infect Dis. 2022 Jun;28(6):1269-1273.

    2. Choudhary ML, Chaudhary U, Salve M, Shinde P, Padbidri V, Sangle SA, Salvi S, Bavdekar AR, D'costa P, Alagarasu K. Functional Single-Nucleotide Polymorphisms in the MBL2 and TLR3 Genes Influence Disease Severity in Influenza A (H1N1)pdm09 Virus-Infected Patients from Maharashtra, India. Viral Immunol. 2022 May;35(4):303-309.

    3. Aggarwal N, Potdar V, Vijay N, Mukhopadhyay L, Borkakoty B, Manjusree S, Choudhary ML, Chowdhury D, Verma R, Bhardwaj SD, Sarmah N, H SK, Kumar P, Gupta N. SARS-CoV-2 and Influenza Virus Co-Infection Cases Identified through ILI/SARI Sentinel Surveillance: A Pan-India Report. Viruses. 2022 Mar 17;14(3):627.

    4. Potdar V, Vipat V, Jadhav S, Saha U, Jadhav SY, Bhardwaj S, Choudhary ML, Cherian S, Abraham P. Detection of SARS-CoV-2 variants in India from UK returnees. Infection. 2021 Dec;49(6):1355-1359.

    5. Tripathy AS, Vishwakarma S, Trimbake D, Gurav YK, Potdar VA, Mokashi ND, Patsute SD, Kaushal H, Choudhary ML, Tilekar BN, Sarje P, Dange VS, Abraham P. Pro-inflammatory CXCL-10, TNF-α, IL-1β, and IL-6: biomarkers of SARS-CoV-2 infection. Arch Virol. 2021 Dec;166(12):3301-3310.

    6. Alagarasu K, Kaushal H, Shinde P, Kakade M, Chaudhary U, Padbidri V, Sangle SA, Salvi S, Bavdekar AR, D'costa P, Choudhary ML. TNFA and IL10 Polymorphisms and IL-6 and IL-10 Levels Influence Disease Severity in Influenza A(H1N1)pdm09 Virus Infected Patients. Genes (Basel). 2021 Nov 28;12(12):1914.

    7. Cherian S, Potdar V, Jadhav S, Yadav P, Gupta N, Das M, Rakshit P, Singh S, Abraham P, Panda S, Team NIC. SARS-CoV-2 Spike Mutations, L452R, T478K, E484Q and P681R, in the Second Wave of COVID-19 in Maharashtra, India. Microorganisms. 2021 Jul 20;9(7):1542.

    8. Bhardwaj SD, Choudhary ML, Gurav YK, Abraham P, Potdar VA. Epidemiological characterization of COVID-19 - Pune, 2020-2021. Indian J Med Res. 2021 May;153(5&6):542-545.

    9. Potdar V, Vipat V, Ramdasi A, Jadhav S, Pawar-Patil J, Walimbe A, Patil SS, Choudhary ML, Shastri J, Agrawal S, Pawar S, Lole K, Abraham P, Cherian S; ICMR-NIV NIC Team. Phylogenetic classification of the whole-genome sequences of SARS-CoV-2 from India & evolutionary trends. Indian J Med Res. 2021 Jan & Feb;153(1 & 2):166-174.

    10. Alagarasu K, Potdar VA, Vipat V, Hundekar S, Gunjikar R, Choudhary ML, Abraham P, Lole KS. Utility of a modified heat inactivation method for direct detection of SARS-CoV-2 by RT-qPCR in viral transport medium bypassing RNA extraction: A preliminary study. Indian J Med Res. 2020 Jul & Aug;152(1&2):108-110.

    11. Potdar V, Choudhary ML, Bhardwaj S, Ghuge R, Sugunan AP, Gurav Y, Yadav PD, Shete A, Tomar S, Anukumar B, Kaushal H, Sapkal G, Basu A, Cherian S, Abraham P. Respiratory virus detection among the overseas returnees during the early phase of COVID-19 pandemic in India. Indian J Med Res. 2020 May;151(5):486-489.

    12. Alagarasu K, Choudhary ML, Lole KS, Abraham P, Potdar V. Evaluation of RdRp & ORF-1b-nsp14 based real-time RT-PCR assays for confirmation of SARS-CoV-2 infection: An observational study. Indian J Med Res. 2020 May;151(5):483-485.

    13. Potdar V, Cherian SS, Deshpande GR, Ullas PT, Yadav PD, Choudhary ML, Gughe R, Vipat V, Jadhav S, Patil S, Nyayanit D, Majumdar T, Walimbe A, Gaikwad S, Dighe H, Shete-Aich A, Mohandas S, Chowdhury D, Sapkal G, Basu A, Gupta N, Gangakhedkar RR, Giri S, Dar L, Jain A, Malhotra B, Abraham P; National Influenza Centre (NIC) Team:. Genomic analysis of SARS-CoV-2 strains among Indians returning from Italy, Iran & China, & Italian tourists in India. Indian J Med Res. 2020 Feb & Mar;151(2&3) :255-260.

    14. Choudhary ML, Vipat V, Jadhav S, Basu A, Cherian S, Abraham P, Potdar VA. Development of in vitro transcribed RNA as positive control for laboratory diagnosis of SARS-CoV-2 in India. Indian J Med Res. 2020 Feb & Mar;151(2&3):251-254.

    15. Sarkale P, Patil S, Yadav PD, Nyayanit DA, Sapkal G, Baradkar S, Lakra R, Shete-Aich A, Prasad S, Basu A, Dar L, Vipat V, Giri S, Potdar V, Choudhary ML, Praharaj I, Jain A, Malhotra B, Gawande P, Kalele K, Gupta N, Cherian SS, Abraham P. First isolation of SARS-CoV-2 from clinical samples in India. Indian J Med Res. 2020 Feb & Mar;151(2 & 3):244-250.

    16. Prasad S, Potdar V, Cherian S, Abraham P, Basu A; ICMR-NIV NIC Team. Transmission electron microscopy imaging of SARS-CoV-2. Indian J Med Res. 2020 Feb & Mar;151(2 & 3):241-243.

    17. Gupta N, Potdar V, Praharaj I, Giri S, Sapkal G, Yadav P, Choudhary ML, Dar L, Sugunan AP, Kaur H, Munivenkatappa A, Shastri J, Kaveri K, Dutta S, Malhotra B, Jain A, Nagamani K, Shantala GB, Raut S, Vegad MM, Sharma A, Choudhary A, Brijwal M, Balakrishnan A, Manjunatha J, Pathak M, Srinivasan S, Banu H, Sharma H, Jain P, Sunita P, Ambica R, Fageria B, Patel D, Rajbongshi G, Vijay N, Narayan J, Aggarwal N, Nagar A, Gangakhedkar RR, Abraham P. Laboratory preparedness for SARS-CoV-2 testing in India: Harnessing a network of Virus Research & Diagnostic Laboratories. Indian J Med Res. 2020 Feb & Mar;151(2&3):216-225.

    18. Yadav PD, Potdar VA, Choudhary ML, Nyayanit DA, Agrawal M, Jadhav SM, Majumdar TD, Shete-Aich A, Basu A, Abraham P, Cherian SS. Full-genome sequences of the first two SARS-CoV-2 viruses from India. Indian J Med Res. 2020 Feb & Mar; 151(2 & 3):200-209.

    19. Bhardwaj SD, Potdar VA, Yadav PD, Chaudhary ML, Chadha MS, Mourya D. A case report of the enterovirus-D68 associated severe acute respiratory illness in a pediatric case from India. J Infect Public Health. 2019 Nov-Dec;12(6):900-903.

    20. Choudhary ML, Alagarasu K, Chaudhary U, Kawale S, Malasane P, Gurav YK, Padbidri V, Kadam D, Sangle SA, Salvi S, Bavdekar AR, D'costa P, Chadha MS. Association of Single Nucleotide Polymorphisms in TNFA and IL10 Genes with Disease Severity in Influenza A/H1N1pdm09 Virus Infections: A Study from Western India. Viral Immunol. 2018 Dec; 31(10):683-688.

    21. Choudhary ML, Anand SP, Tikhe SA, Walimbe AM, Potdar VA, Chadha MS, Mishra AC. Comparison of the conventional multiplex RT-PCR, real time RT-PCR and Luminex xTAG® RVP fast assay for the detection of respiratory viruses. J Med Virol. 2016 Jan; 88(1):51-7.

    22. Choudhary ML, Anand SP, Sonawane NS, Chadha MS. Development of real-time RT-PCR for detection of human metapneumovirus and genetic analysis of circulating strains (2009-2011) in Pune, India. Arch Virol. 2014 Feb;159(2):217-25.

    23. Choudhary ML, Anand SP, Wadhwa BS, Chadha MS. Genetic variability of human respiratory syncytial virus in Pune, Western India. Infect Genet Evol. 2013 Dec; 20:369-77.

    24. Choudhary ML, Wadhwa BS, Jadhav SM, Chadha MS. Complete Genome Sequences of Two Human Respiratory Syncytial Virus Genotype A Strains from India, RSV-A/ NIV1114046/11 and RSV-A/NIV1114073/11. Genome Announc. 2013 Jul25;1(4) :e00165-13.

    25. Choudhary ML, Anand SP, Heydari M, Rane G, Potdar VA, Chadha MS, Mishra AC. Development of a multiplex one step RT-PCR that detects eighteen respiratory viruses in clinical specimens and comparison with real time RT-PCR. J Virol Methods. 2013 Apr;189(1):15-9.

    26. Mishra AC, Chadha MS, Choudhary ML, Potdar VA. Pandemic influenza (H1N1) 2009 is associated with severe disease in India. PLoS One. 2010 May 7;5(5):e10540.

    27. Iyer JP, Kaprakkaden A, Choudhary ML, Shaha C. Crucial role of cytosolic tryparedoxin peroxidase in Leishmania donovani survival, drug response and virulence. Mol Microbiol. 2008 Apr;68(2):372-91.

    28. Sharma R, Sharma PR, Choudhary ML, Pande A, Khatri GS. Cytoplasmic expression of mature glycylglycine endopeptidase lysostaphin with an amino terminal hexa-histidine in a soluble and catalytically active form in Escherichia coli. Protein Expr Purif. 2006 Jan;45(1):206-15.

    29. Choudhary ML, Jawaid S, Ahuja MK, Shiva NK, Gupta P, Bhuyan AK, Khatri GS. Open reading frame yjbI of Bacillus subtilis codes for truncated hemoglobin. Protein Expr Purif. 2005 Jun;41(2):363-72.

 

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